Frederick P. Rose Teaching Laboratory provides a hands-on learning experience for biomedical engineering majors. It is located in the Daniel L. Malone Engineering Center, a key and architecturally dramatic component in Yale's $500 million commitment to science and engineering. The Malone Center is a 64,700 sq. foot laboratory building. Construction was completed in 2005 and achieved a LEED Gold rating in 2006. The center houses the Department of Biomedical Engineering, which brings together in full partnership faculty from Yale Engineering and the School of Medicine. With an important goal of linking the laboratory research to the clinical environment, the department addresses a range of health-care issues, among them design of biomaterials for tissue engineering, development of drug delivery systems to treat cancer, development of nanoparticles that are targeted to cells in the immune system, analysis of cell and tissue structure with multiphoton microscopy, and use of integrated anatomical and functional imaging to guide neurosurgical procedures. In addition to research, the Malone Center offers state-of-the-art facilities for undergraduate education. Designed to be comfortable, practical, elegant, and high-tech, the interior of the building sets a new standard of excellence for Yale's laboratories. Researchers have ready access to the latest equipment, computers and communications technology. Equally important, the building was designed so that laboratories can be easily reconfigured as the needs of researchers evolve over time.